Standard complete blood counts (CBC) frequently miss early iron depletion because hemoglobin levels remain normal until bone marrow reserves are entirely exhausted.
Mayo Clinic hematological benchmarks emphasize that serum ferritin should be maintained between 50 and 100 ng/mL for optimal mitochondrial function and cognitive vitality. Women experiencing heavy menstrual flow require bioavailable, non-constipating iron bisglycinate alongside Vitamin C co-factors.