While the circadian rhythm governs our 24-hour sleep-wake cycle, female physiology is governed simultaneously by the infradian rhythm—a 28-day biological clock that drives systemic shifts in metabolic rate, neurotransmitter synthesis, and cellular repair.
Clinical research from Harvard Medical School indicates that insulin sensitivity fluctuates dramatically across monthly phases, peaking during the follicular phase and declining in the luteal window as progesterone surges. Aligning nutritional intake and physical output with these biological phases stabilizes energy and mitigates chronic adrenal burnout.